Sibutramine (Meridia) Appetite Suppressants, Raises Seratonin Levels
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Sibutramine Reduces Appetite
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What is Sibutramine?
====================

Sibutramine (Meridia) is one of the new classes of appetite
suppressants. It also works on the brain's appetite center - making it
think the stomach is full - by raising levels of seratonin, an
important neurotransmitter in the brain.

In clinical studies involving 6000 obese people, Meridia resulted in
an average 5 percent to 10 percent weight loss over 1 year.

People who have a history of stroke, heart disease, congestive heart
failure, or uncontrolled high blood pressure should not use Meridia.

Although this drug was not associated with heart-valve abnormalities,
it can cause significant elevation in blood pressure in some people.

The drug manufacturer, Knoll Pharmaceutical Co., is urging physicians
to carefully monitor the blood pressure of all patients taking
Meridia.



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