At best, the consumer is provided with and reads an extremely pared down version of the DPI. It is vital that everyone should read the entire DPI, whether you understand all the jargon or not. You can print any of the documents below. Your pharmacist should be able to answer very technical questions and would be a good impartial source.
DPI's Updated 7/19/07
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NOTE: When you display FDA Medwatch DPI links, changes are
HIGHLIGHTED in YELLOW.
Advicor by KOS
Pharmaceuticals
Niacin Extended-Release
& Lovastatin ~ Reduces LDL cholesterol & triglycerides, raises HDL ~ May
cause an increase in blood sugar levels (caution for diabetics) ~
Revised: April,
2007
Caduet (Amlodipine Besylate/Atorvastatin Calcium) Tablets by Pfizer
CADUET is a combination of two drugs, a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) amlodipine (antihypertensive/antianginal agent) and an HMG-CoA reductase inhibitor atorvastatin (cholesterol lowering agent).
Crestor ~ Public Citizen Warning:
Petition to the FDA to remove Crestor from the market.
Page down to the "Reader Comments".....
Crestor (Rosuvastatin Calcium) Tablets by AstraZeneca
Synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.
Revised: January, 2007
Lescol/XL (Fluvastatin Sodium) Capsules/Tablets by Novartis
Fullu Synthetic HMG-CoA reductase inhibitor and is hydrophilic.
Revised: April 2006
Lipitor (Atorvastatin Calcium) Tablets by Pfizer
Synthetic lipid-lowering agent. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, an early and rate-limiting step in cholesterol biosynthesis.
Revised: March, 2007
Lopid (Gemfibrozil) Tablets by Pfizer
LOPID is a lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol, and increases high density lipoprotein (HDL) cholesterol. While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with LOPID therapy, treatment of patients with elevated triglycerides due to Type IV hyperlipoproteinemia often results in a rise in LDL-cholesterol.
FDA Medwatch: March, 2004
Mevacor (Lovastatin) Tablets by Merck
Cholesterol lowering agent isolated from a strain of Aspergillus terreus.
Revised: May, 2007
Pravachol (Pravastatin Sodium) Tablets by Bristol Myers Squibb
New class of lipid-lowering compounds, the HMG-CoA reductase inhibitors, which reduce cholesterol biosynthesis.
Revised: March, 2007
FDA Medwatch Document (33 pages) July 2005
Tricor (Fenofibrate) Tablets by Abbott
Tricor is used to lower triglyceride (fat-like substances) levels and cholesterol levels in the blood. Revised: November, 2004
Vytorin is a combination of Zetia (Ezetimibe) & Zocor (Simvastatin)
Ezetimibe is a selective inhibitor of intestinal cholesterol and related phytosterol absorption, and Simvastatin is a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor.
Revised: May, 2007
Zetia (Ezetimibe) Tablets by Merck
ZETIA is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols.
Revised: June, 2007
Zocor (Simvastatin) Tablets by Merck
Lipid-lowering agent that is derived synthetically from a fermentation product
Revised: August, 2005