Here are some amusing comments from an Internet discussion on who would win, Leonard "Bones" McCoy or Temperance "Bones" Brennan. I chuckled.
Bones, of course.
Dammit, Jim, I'm a doctor not a fighter.
One of them has Romulan ale and Saurian brandy. The other has breasts. Tough choice but I still say "Bones".
One Bones is a wannabe cop who feeds flesh-eating beetles on corpses of the recently dead, before turning said corpses over to their families for burial. (Fox TV show)
The other has a pill that regrows kidneys. (Star Trek Voyage Home) He wins.
Bones has a cuter sidekick than Bones.
Okay, so Bones is a doctor, not a prizefighter. Still, he's presumably had hand-to-hand combat training, and he's held his own in many a fracas. He also knows how to wield a firearm.
Bones is also a brilliant surgeon. He was (or will be?) perhaps the most highly accomplished medical officers in Starfleet. With just a few bag of thermoconcrete, he can practically cure a rainy day.
Bones, on the other hand, has tantalizing eyes and porcelain skin. She's smokingly hot.
Tough call.