Lp299v
A New Start for IBS
Autism and LP299V
Lp299v the unique probiotic based on a specific strain of lactobacillus plantarum and supported by two high quality research papers to be effective in managing the symptoms associated with Irritable Bowel Syndrome, is now gaining further support from User testimonials include: “I can’t believe how quickly I noticed an improvement. Normally it takes a couple of days to calm things down, but with Lp299v it was pretty much straight away”. “Constipation did not improve, but the pain and bloating noticeably improved. If I don’t take the capsules for one or two days, it’s back”. “I generally found that my symptoms eased and I more regularly pass a ‘normal’ stool”. “Overall my situation has calmed down, but I still have sessions of diarrhoea and constipation. It’s just that the times between these attacks seem to be less painful and less windy”. “Still having some symptoms, but improving”. “I have been taking Lp299v for some months now and my IBS has almost disappeared. When I ran out a few months back, I soon went back to bloating, pain, excessive wind etc..I will be on these for life. They are a Godsend. Thanks”. Harvard Clinic Scientist Finds Gut and Autism Link
Dr. Timothy Buie, a pediatric gastroenterologist from Harvard/Mass General Hospital has performed over 400 gastrointestinal endoscopies with biopsies, as well as evaluation of digestive enzyme function in children diagnosed with autism and finding a connection. The results of his testing are similar to the observations made by Dr. Andrew Wakefield regarding the presence of chronic inflammation of the intestinal tract, although the incidence was noted to be less frequent in his group.
Dr. Buie announced his findings last Saturday at the Oasis 2001 Conference for Autism in Portland, Oregon, the day before the announcement of Wakefield's forced departure from Royal Free in the UK.
The biopsy results indicated the presence of chronic inflammation of the digestive tract including esophagitis, gastritis and enterocolitis along with the presence of Iymphoid nodular hyperplasia in 15 of 89 children. Additionally the results of the enzyme testing of Dr. Buie’s patients paralleled that of Dr. Karoly Horvath and colleagues at the University of Maryland School of Medicine. Dr. Buie found that the autistic children he examined showed disaccbaride/glucoamylase enzyme levels below normal. Some 55% of these children had lactase deficiencies (which breaks down lactose in milk) as well as deficiencies of the enzyme sucrase (responsible for digestion of table sugar).
The findings also lend support to anecdotal reports of improvement of some autistic children on wheat and dairy (gluten, casein) free diets. Buie says that Harvard wants to do research into the use of protein enzyme supplements, which aid in the digestion of wheat and milk products for treatment.
Buie echoed the opinion of other a growing number of clinical researchers and practitioners treating autistic patients, "these children are ill, in distress and pain, and not just mentally, neurologically dysfunctional."
Gastrointestinal Dysfunction and Autism
A number of investigators have reported that a significant percentage of autistic children present with gastrointestinal symptoms including diarrhea, constipation, abdominal pain, reflux, gaseousness, and/or foul smelling stools. The fraction of autistic children that show one or more of these symptoms has not been well documented but a recently reported survey suggests it exceeds 50% (Gastroenterology, 1999, v116, abstract G2433). Furthermore, elevated intestinal permeability measured by the lactulose/mannitol test was observed in 43% of autistic children not presenting with clinical gastrointestinal symptoms (D'Eufemia et. al., 1996, Acta Paediatrica, v85, p1076). Additional evidence of abnormal intestinal permeability is the observation of peptiduria in autistic children (Reichelt, K.L., Dev. Brain Dysfunction, 1994, v4, pp. 71-85).
Wakefield et. al. have characterized an inflammatory/immune response in the colon and ileum of autistic children which has been termed “autistic enterocolitis”. An initial report characterized an lymphoid nodular hyperplasia and intestinal inflammation in 12 autistic children (Lancet 1998, v351, p637). These preliminary observations have now been extended to 60 children and additional documentation of the inflammatory enterocolitis through endoscopic and histologic measures have been made (Wakefield, A.J. et. al., submitted; Furlano, A. et. al., submitted).
In addition, Horvath et. al. have carried out histologic examinations of 36 autistic children with gastrointestinal symptoms. In this study 69% had grade I or II reflux esophagitis, 42% had chronic gastritis and 67% had chronic duodenitis (Horvath, K., et. al., Journal of Pediatrics, 1999, 135: 559-63).
Thus there is a growing body of evidence that a unique pattern of gastrointestinal dysfunction exists in a large fraction of children diagnosed with autism.
To purchase LP299V CLICK HERE
ONLY £18.99
