Multiple Sclerosis
Multiple sclerosis (MS) is a chronic, long-term condition that affects the central nervous system, which includes the brain and spinal cord. MS is an autoimmune disease, which means that the body's immune system mistakenly attacks itself, targeting the cells, tissues, and organs.
Multiple sclerosis is a part of the family of autoimmune diseases that includes:
- Rheumatoid arthritis
- Psoriasis
- Type 1 diabetes
- Lupus
- Crohn's disease
Scientists now believe that multiple sclerosis results from an abnormal response to an infection or an environmental factor. Numerous studies show that genetics may play a role in the development of multiple sclerosis, but are not the sole cause of the disease.
Multiple sclerosis affects over 400,000 people in the US, and may affect 2.4 million people worldwide.
What causes multiple sclerosis?
Despite a great deal of research, the exact cause of multiple sclerosis has not yet been discovered. However, evidence suggests that environmental factors and infectious agents such as viruses and bacteria have been proposed as triggers.
Although there is currently no way to decrease a person’s risk of developing multiple sclerosis, we know that risk is slightly higher if a parent or sibling has it.
How is Multiple Sclerosis Diagnosed?
No one test can identify or rule out multiple sclerosis. Your healthcare provider may want you to have several tests or procedures. Most of them are painless.
A multiple sclerosis diagnosis usually begins with a complete neurological examination and a discussion of your full medical history with your healthcare provider. He or she will need an overall view of your health, including your symptoms and when they started. However, it may still be difficult, if not impossible, to confirm the presence of multiple sclerosis without using certain procedures.
Many healthcare providers use magnetic resonance imaging (MRI) to help diagnose MS at an early stage by providing a detailed picture of the brain. Early diagnosis means that treatment can begin right away, rather than waiting for continued relapses to confirm diagnosis.
Other tests for multiple sclerosis may include:
- Evoked potential tests, which measure how a person’s nervous system responds to certain stimulation
- Spinal tap, which checks spinal fluid for signs of multiple sclerosis
Your healthcare provider will determine which test is best suited for the type of symptoms that you have.
Multiple Sclerosis SymptomsMultiple sclerosis (MS) can cause a wide range of symptomsmultiple sclerosis symptoms. Some problems occur often, and some are seldom seen. The course of illness is different for each person. Even when there are no symptoms, there is progression of damage to the central nervous system over time. That's why it is important to stay on your multiple sclerosis treatment. Common multiple sclerosis symptoms are: Optic NeuritisThis multiple sclerosis symptomsis an inflammation of the optic nerve, the nerve that controls the eye. Over a period of days, you may develop blurred vision. Sometimes you may feel pain behind your eye, which increases when you turn your eye. After initial symptoms, there is gradual improvement, sometimes after several weeks. But recovery is not always complete. During periods of stress, fatigue or fever, the blurred vision in the eye may return. This does not necessarily mean that the multiple sclerosis is active again. Rather, it may be the result of permanent disability that has accumulated over time. Loss of Muscle Strength in Arms and LegsThe nervous system contains large numbers of nerve fibers that control movement - what we call motor function. Often, multiple sclerosis is active on the nerve fibers that control muscle movement. Many people with multiple sclerosismultiple sclerosis symptoms lose muscular strength in the arms and legs as the disease progresses. The loss can range from reduced dexterity (the fingers no longer work so well) to paralysis of an arm or leg. Loss of muscular strength occurs not only in the form of relapses (temporary attacks) but also as a gradual (progressive) process without recovery. Gradual loss of strength occurs more frequently in the legs than in the arms. Depending on the severity, you may need to rely on a cane, crutches, or even a wheelchair to get around. Change in Sense of TouchThe vast nervous system includes many sensory nerve fibers dedicated to helping you be aware of your environment. They provide the sense of touch in your fingers, and your ability to feel cold or heat on all parts of your body. When these fibers are damaged through multiple sclerosis, your sense of touch may be replaced by feelings of numbness or tinglingmultiple sclerosis symptoms. Parts of your body may feel burning or cold, even though there is no heat or chill present. Symptoms multiple sclerosis symptomscan be temporary (relapses) or more progressive, and can occur in various parts of the body. This could be just one part of an arm or leg, in the whole lower half of the body, say below the navel, or in a collection of numb patches occurring randomly all over the body. PainMultiple sclerosis can be accompanied by various kinds of painmultiple sclerosis symptoms. Damage to the sensory tracts in the spinal cord can result in burning pain in the arms and legs. Multiple sclerosis can often result in damage to the nerves of the face, a painful condition known as "trigeminal neuralgia." If multiple sclerosis has impaired your ability to walk, the extra strain in the muscles of your back and legs can become painful. Multiple sclerosis can also cause extra tension in the muscles of your arms and legs: this is known as "spasticity" and can also be painful. Bladder/Bowel ProblemsMany people with multiple sclerosismultiple sclerosis symptoms will develop trouble controlling the urge to urinate or will be unable to completely empty the bladder. Less frequently, they will also experience problems with bowel control. As multiple sclerosis progresses and you develop a more sedentary lifestyle, you may also be troubled with constipation. Sexual DysfunctionHaving multiple sclerosis can lead to problems related to sexual activitymultiple sclerosis symptoms, especially if your bladder or bowels are already affected. Men with multiple sclerosis can find it difficult to achieve or maintain an erection. In women, multiple sclerosis often causes a loss of sexual sensitivity, pain during intercourse, an inability to achieve an orgasm, or a reduction in naturally produced lubrication. Balance/Coordination ProblemsThe part of the brain known as the cerebellum controls and corrects all our movements. Damage from MS can result in poor balance or coordination. You may, for instance, have difficulty grasping small objects, writing clearly, or keeping a steady hand. When walking across a room, you may find yourself losing your balance, as if you were intoxicated. Like most other multiple sclerosis symptoms, these problems can be temporary (during a relapse), or they can be a permanent result of the progression of multiple sclerosis. FatigueMany people with multiple sclerosis experience fatigue or tirednessmultiple sclerosis symptoms. But since fatigue can be a sign of so many other diseases, too, it is not often immediately identified as being caused by multiple sclerosis. Fatigue occurs in both relapsing multiple sclerosis and in the more progressive types of the disease. It can often last for a few months during which time your energy is used up every day with just a little exertion. Changes in Cognitive FunctionAt some point in the course of your illness with multiple sclerosis, you may notice changes in cognitive function, such as your memory and speed of thinking. You may also have difficulty concentrating, making it hard for you to focus your attention. In some patients these multiple sclerosis symptomssymptoms can occur early in the disease; in others, they can come later.Mood ChangesMany people with multiple sclerosis experience periods of depression. Sometimes it is linked directly to physical changes in the brain caused by multiple sclerosis. Understandably, it may also be an emotional reaction to having the illness and learning to cope with the symptomsmultiple sclerosis symptoms and the challenges they represent. If you are experiencing feelings or symptoms multiple sclerosis symptomsof depression or hopelessness, discuss them with your doctor because treatment for depression is available. Multiple sclerosis is a diagnosis that can be made only after every other possible explanation of the signs and symptoms has been ruled out. There are a number of medicines available to help manage multiple sclerosis. They fall into two basic categories:
Talk with your healthcare provider about the best treatment option for you. |