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Breast implant infection with Mycobacterium fortuitum group: Report of case and review

A prosthetic breast implant infected with Mycobacterium fortuitum.

Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants.

Periprosthetic mycobacterial infection. CT and mammographic findings.




Journal of Infection
Volume 52, Issue 3 , March 2006, Pages e63-e67

Copyright © 2005 The British Infection Society Published by Elsevier Ltd.

Case Report

Breast implant infection with Mycobacterium fortuitum group:

Report of case and review

Donald C. Vinha, Assunta Rendinab, Robert Turnerc and John M. Embild, Corresponding Author Contact Information, E-mail The Corresponding Author

aSection of Infectious Diseases, Department of Medicine,

University of Manitoba, Winnipeg, Man., Canada


bClinical Microbiology Laboratory, Health Sciences Centre,

Winnipeg, Man., Canada


cSection of Plastic Surgery, Department of Surgery,

University of Manitoba, Winnipeg, Man., Canada


dSection of Infectious Diseases, Department of Medicine,

University of Manitoba, Winnipeg, Man., Canada

Accepted 23 July 2005.  Available online 19 September 2005.

Summary

There has been a marked increase in the frequency with which breast prosthesis are being used,

 both for reconstructive and cosmetic purposes. Although breast implant-related infections are

uncommon, they are typically caused by bacterial skin flora, specifically Staphylococcus aureus

 and the coagulase negative staphylococci. There have been infrequent reports of breast implant

 infection caused by the atypical mycobacteria. This report summarizes the case of a young female

who underwent augmentation mammoplasty who presented shortly thereafter with clinical evidence

 of an infected breast prosthesis. Despite a protracted course of empiric antibiotic therapy and multiple

 surgical interventions, she failed to improve. Additional microbiologic investigations allowed for a

diagnosis of Mycobacterium fortuitum group breast implant infection to be established. A prolonged

 course of anti-mycobacterial therapy, based upon susceptibility results, allowed for eradication of the

 infection and subsequent successful re-implantation of the prosthesis.

Keywords: Breast implant; Infection; Atypical mycobacteria; Mycobacterium fortuitum

Corresponding Author Contact InformationCorresponding author. Address: Infection Control Unit, Health Sciences Centre,

MS673-820 Sherbrook Street, Winnipeg, Man., Canada R3A 1R9.

Tel.: +1 204 787 4654; fax: +1 204 787 4699.

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 Ann Plast Surg. 2000 Mar;44(3):330-3.

A prosthetic breast implant infected with Mycobacterium fortuitum.

  • Heistein JB,
  • Mangino JE,
  • Ruberg RL,
  • Bergese JJ.

Division of Plastic Surgery, Ohio State University, Columbus 43210, USA.

Augmentation mammaplasty is a common operation performed in the United States. Postoperative wound infections are rare, but can be devastating. Most often, bacteria from the normal skin flora cause these infections, but more atypical organisms can lead to similar situations. The authors present a case of a prosthetic breast implant infected with Mycobacterium fortuitum after augmentation mammaplasty. The patient, diagnosis, and treatment are discussed so that others may recognize and treat this entity successfully before encountering major complications. Although it is an infrequent occurrence, plastic surgeons, infectious disease specialists, and primary care doctors who may see postoperative wound infections should be aware of this potential pathogen. It is important in any postimplant infection and especially crucial in cases of unresolving or recurrent infections with unusual or even clear drainage. With proper identification through acid-fast smear and culture, multiagent therapy can be initiated early. Additional complications, including implant removal, may thus be avoided.

PMID: 10735228 [PubMed - indexed for MEDLINE]

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Plast Reconstr Surg. 1995 Jan;95(1):142-4.

Localized Mycobacterium avium-intracellulare mastitis in an immunocompetent woman with silicone breast implants.

Lee D, Goldstein EJ, Zarem HA.

Department of Family Practice, Santa Monica Hospital Medical Center, Calif.

While M. avium-intracellulare has received increasing recognition due to its association with AIDS, silicone breast implants have come under increased FDA scrutiny, requiring new safety and efficacy protocols. We report a case of localized M. avium-intracellulare mastitis associated with a breast implant in an immunocompetent, HIV-negative woman who was cured with implant removal and a long course (6 months) of clarithromycin. Serous exudates occurring in association with breast implants should be cultured for acid-fast organisms. Clarithromycin may be a therapeutic adjunct to effectively cure these infections.

Publication Types:
  • Case Reports

PMID: 7809228 [PubMed - indexed for MEDLINE]

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 Clin Imaging. 1995 Jul-Sep;19(3):193-6.

Periprosthetic mycobacterial infection. CT and mammographic findings.

  • Walsh R,
  • Kliewer MA,
  • Sullivan DC,
  • Hertzberg B,
  • Paulson EK,
  • Soo MS,
  • Saksouk FA,
  • Kornguth PJ.

Duke University Medical Center, Department of Radiology, Durham, NC 27710, USA.

Organisms of the Mycobacterium fortuitum complex are an uncommon but important cause of periprosthetic infection following augmentation mammoplasty or other breast surgery. This etiological agent must be considered in the particular case of periprosthetic infection, because special handling of the fluid is crucial to enhance recovery of the organism. We describe the computed tomography (CT) and mammographic findings in such an abscess with respect to the clinical context and subsequent management. To our knowledge, CT findings associated with any periprosthetic breast infection have not been described.

PMID: 7553436 [PubMed - indexed for MEDLINE]

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