Histol Histopathol. 1997 Oct;12(4):1003-11.

Silicone granulomatous lymphadenopathy and siliconomas of the breast.

Vaamonde R, Cabrera JM, Vaamonde-Martín RJ, Jimena I, Marcos Martín J.

Department of Morphological Sciences, College of Medicine, University of Córdoba, Spain.

In the present study, two histologically-distinct cases of granulomatous lymphadenitis induced by dimethylpolysiloxane (silicone polymer) implants were studied. Four and six years after implant, and following surgery for breast cancer, painful homolateral axillary adenopathies were observed and biopsied. In both cases, histological examination led to a diagnosis of "silicone-induced granulomatous adenitis" requiring removal of implants. Foreign-body granulomas (siliconomas) were observed in surrounding tissue with no apparent rupture of implant capsules; however, visible retraction, hardening and scattered calcifications were noted. The presence of silica was revealed by incineration of a number of biopsied lymph nodes, a technique not hitherto used in the study of this pathology. A review is offered of the literature available.

Br J Plast Surg. 2001 Apr;54(3):257-9.

Expanding silicone granuloma.

Malyon AD, Dunn R, Weiler-Mithoff EM.

Plastic Surgery Unit, Canniesburn Hospital, Switchback Road, Bearsden, Glasgow G61 1QL, UK.

Complications of breast augmentation using silicone implants have been the subject of much discussion. We report a single case of a silicone granuloma, which has exhibited unusual behaviour in that it has grown rapidly and significantly. Whilst silicone granulomata have been reported on many occasions in the past, to our knowledge this is the first report of a rapidly growing example. Copyright 2001 The British Association of Plastic Surgeons.

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