Radiology. 1983 Oct;149(1):69-72

Destructive arthritis due to silicone: a foreign-body reaction.

Rosenthal DI, Rosenberg AE, Schiller AL, Smith RJ.

The authors report 3 cases of erosive arthritis resulting from a foreign-body reaction to a silicone implant in the wrist. No patient had a history of inflammatory arthritis. Radiographic changes included well-defined lytic lesions with thin, sclerotic margins, normal mineralization, and loss of volume of the implant. Pathologically, a destructive foreign-body reaction was seen, with intra- and extracellular silicone debris.

PMID: 6351165 [PubMed - indexed for MEDLINE]

http://radiology.rsnajnls.org/cgi/reprint/149/1/69

Implant Research

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