Aesthetic Plast Surg. 2002 Sep-Oct;26(5):383-7.

Rupture of a silicone gel mammary prosthesis and amyloidosis: a case report.

Emekli U, Tümerdem B, Demiryont M.

There has been a great deal of controversy regarding the safety of silicone breast implants. Silicone gel prostheses older than 10 years have the risk of either leakage or outright rupture. The role of silicone gel in relation to connective tissue disease or amyloidosis has not been proved by current serologic, immunologic, or epidemiologic tests. In this paper, we present a case with renal amyloidosis and a history of untreated silicone implant rupture for five years.

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