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These nerves contain the carboxylase enzyme that converts 5HTP to serotonin, but not the hydroxylase enzyme that coverts tryptophan to 5HTP.

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I understand this, but, there could be other mechanisms that are less efficient and that burn food less efficiently.

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This exacerbation of concern was triggered mainly by the publication of the poorly done SMART trial and what I believe to be a flawed and overblown meta-analysis in the Annals of Internal Medicine by Salpeter.

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