ThatGuyWithTheGlasses - Lots of hilarious videos, 'Home of "5 Second Movies" and "Nostalgia Critic"'.
The Spoony Experiment - A site run by Noah Antwiler, he makes extremely funny movie and game reviews.
I-Mockery - The site is just fantastic, funny and fantastic. Go!
Doc Mock's Movie Mausoleum - A show somewhat similar to Mystery Science Theater 3000, airs live every Friday 10PM PST (1AM EST). You can find the link to the live stream and to archived episodes at TheStream.tv.
ScrewAttack - A ginormous gaming community with tons of informative and funny content.
Artificial Raven's Domain - A pal who also has gaming videos on YouTube. Go check his site out, it looks much nicer than mine.